Feb 15 1999;132(2-3):139-46
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In BV2 and N2a cells treated with amyloid (A), berberine promotes cell proliferation, inhibits the activity of caspase-3, and reduces the rate of apoptosis, in addition, berberine promotes cell viability via the microRNA (miR)-188/nitric oxide synthase 1 (NOS1) pathway (Ye et al., 2009
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The anti-aging skin claims are supported by in vitro, animal, and observational human data, which is consistent with what providers and patients report clinically
In a human hair follicle organ culture model, AHK-Cu demonstrated three key effects at concentrations of 10^-12 to 10^-9 M (extremely low doses) (Pyo et al., Arch Pharm Res, 2007)